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Despite the success of glucagon-like peptide-1 receptor agonists (GLP-1RAs), many patients fail to achieve or sustain sufficient weight reduction with current therapies

They may cause side effects like nausea or vomiting and are not suitable for people with specific health conditions, such as a history of certain types of thyroid cancer or severe digestive disorders

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188 In another study conducted in male smokers, high serum cysteine levels were associated with gastric adenocarcinomas but not with oesophageal squamous cell carcinomas 189 or head and neck squamous cell carcinoma

Here are the BMI requirements for each GLP-1 medication: Mounjaro is FDA-approved to treat type 2 diabetes